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IJE Advance Access published online on August 27, 2007

International Journal of Epidemiology, doi:10.1093/ije/dym165
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2007; all rights reserved.

Cohort profile: The Adventist Health Study-2 (AHS-2)

Terry L Butler1,*, Gary E Fraser1, W Lawrence Beeson1, Synnøve F Knutsen1, R Patti Herring1, Jacqueline Chan1, Joan Sabaté1, Susanne Montgomery1, Ella Haddad1, Susan Preston-Martin2, Hannelore Bennett1 and Karen Jaceldo-Siegl1

1 School of Public Health, Loma Linda University, Loma Linda, California, USA.
2 School of Medicine, University of Southern California, Los Angeles, California, USA.

* Corresponding author. School of Public Health, Loma Linda University, 24785 Stewart Street, Room 203, Loma Linda, California 9235, USA. E-mail: tbutler@llu.edu

The first 150 words of the full text of this article appear below.


    How did the study come about?
 
The Adventist Health Study-2 (AHS-2) began in 2002 with the goal of investigating the role of selected foods to change the risk of cancer. AHS-2 is designed to provide more precise and comprehensive results than previous pioneering research among Seventh-day Adventists1–6, a unique health oriented population with diverse dietary habits.

The Adventist church, of 24 million adherents world-wide, promotes a healthy lifestyle. Church members are expected to be non-smokers and non-alcohol users, and are encouraged to eat a vegetarian diet. Many also avoid caffeine-containing beverages. However, adherence to these recommendations is quite variable.

Adventists in North America are almost entirely a non-smoking population. The vast majority are non-drinkers and the small number who consume alcohol do so infrequently. But they have a wide diversity in dietary practices. Two previous longitudinal studies in California showed a small percentage are total vegetarians, many follow a lacto-ovo-vegetarian diet or eat meat less . . . [Full Text of this Article]


    What does it cover?
 

    Who is in the sample?
 

    Enrolment methods
 

    How often will study subjects be followed-up?
 
Morbidity and mortality follow-up
Tumour registry matching
Hospital history form
Clinics in churches

    What has been measured?
 
Main questionnaire
Calibration study

    What is the rate of loss likely to be?
 

    What has AHS-2 found?
 

    What are the main strengths and weaknesses?
 

    Where can I find out more and what is the potential for collaboration?
 

    Supplementary data
 

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