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IJE Advance Access first published online on July 30, 2007
This version published online on August 1, 2007
International Journal of Epidemiology, doi:10.1093/ije/dym083
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2007; all rights reserved.

Commentary: Trajectories, Selection and Cumulative Causation

Andrew Pickles

Biostatistics, Informatics and Health Economics Group, School of Community Medicine, University of Manchester, England.

E-mail: andrew.r.pickles@manchester.ac.uk

Accepted 22 March 2007

The first 10% of the full text of this article appears below.

Recent advances in life-course epidemiology have been considerable. Researchers now have a taste for examining a range of questions that involve contrasting combinations of patterns of exposure and patterns of impact on health outcomes that may be distant or occur over an extended time period, and data sets are becoming available where such questions can potentially be feasibly addressed.1,2 However, the statistical frameworks in which such ideas can be formalized and tested are currently limited in . . . [Full Text of this Article]


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