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IJE Advance Access published online on January 17, 2007
International Journal of Epidemiology, doi:10.1093/ije/dyl303
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2007; all rights reserved.

Commentary: Assessing the effects of the Scottish Smokefree Law—the placebo effect and the importance of obtaining unbiased data*

Stanton A Glantz

University of California, San Francisco, CA 9413-1390, USA. E-mail: glantz@medicine.ucsf.edu

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The placebo effect, when patients report feeling better after receiving a treatment even though the treatment has no real benefit, is a well-known pitfall in clinical trials. To avoid reporting misleading or incorrect results in trials, when possible investigators blind the subjects to the treatment and seek objective measures of outcome that are unaffected by the experimental subjects’ beliefs. The need for objective outcome measures is particularly important when it is not possible to blind the experimental subjects. The paper by Adda et al.1 of perceived . . . [Full Text of this Article]


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