Skip Navigation



IJE Advance Access published online on November 3, 2005
International Journal of Epidemiology, doi:10.1093/ije/dyi213
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
35/1/181    most recent
dyi213v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Related articles in Int. J. Epidemiol.
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Park, H. S.
Right arrow Articles by Cho, S.-I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Park, H. S.
Right arrow Articles by Cho, S.-I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2005; all rights reserved.
Accepted September 26, 2005

Original paper

Obesity has a greater impact on cardiovascular mortality in younger men than in older men among non-smoking Koreans

Hye Soon Park 1, Yun-Mi Song 2, and Sung-Il Cho 3*

1 Department of Family Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
2 Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea
3 Institute of Health and Environment, School of Public Health, Seoul National University, Seoul, Korea

* To whom correspondence should be addressed.
Sung-Il Cho, E-mail: scho{at}snu.ac.kr


  Abstract

Introduction We investigated the effects of age on the relationship between body mass index (BMI) and cardiovascular risk factors and cardiovascular mortality in non-smoking Korean men.

Methods We performed a prospective cohort study of 246 146 non-smoking Korean men aged 20-69 years at baseline (1992) who were initially without history of cancer or weight change. The associations between BMI and cardiovascular risk factors and mortality during an 9-year follow-up period (2000) were stratified by age group after adjustment for family history, alcohol consumption, exercise habits, and economic status.

Results Calculations of odds ratios (ORs) revealed that younger men (<40 years) with greater BMI (≥28 kg/m2) were at greater risk of high blood pressure, high blood glucose, and high total cholesterol than older men. The ORs for cardiovascular risk factors associated with greater BMI declined linearly with age. The relative risks for mortality from stroke and from all cardiovascular diseases associated with greater BMI were also higher among younger men and declined linearly with age.

Conclusions The cardiovascular risk factors and mortality associated with greater BMI were higher among younger than older non-smoking Korean men. These findings indicate that obesity has a greater impact among younger men with respect to premature cardiovascular related deaths.

Keywords: Obesity; cardiovascular risk factors; mortality; age effect.
A Commentary has been commissioned to accompany this paper and will appear with this article in the printed issue.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?

Related articles in Int. J. Epidemiol.:

Commentary: Obesity and cardiovascular disease risk among the young and old--is BMI the wrong benchmark?
Alan J. Flint and Eric B. Rimm
Int. J. Epidemiol. 2006 10.1093/ije/dyi298. [Abstract]  



This article has been cited by other articles:


Home page
 Arch Intern MedHome page
D. Mozaffarian, A. Kamineni, R. J. Prineas, and D. S. Siscovick
Metabolic Syndrome and Mortality in Older Adults: The Cardiovascular Health Study
Arch Intern Med, May 12, 2008; 168(9): 969 - 978.
[Abstract] [Full Text] [PDF]

Home page
 Int J EpidemiolHome page
C. Sauvaget, K. Ramadas, G. Thomas, J. Vinoda, S. Thara, and R. Sankaranarayanan
Body mass index, weight change and mortality risk in a prospective study in India
Int. J. Epidemiol., April 3, 2008; (2008) dyn059v1.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
J.-W. Kwon, Y.-m. Song, H. s. Park, J. Sung, H. Kim, and S.-i. Cho
Effects of Age, Time Period, and Birth Cohort on the Prevalence of Diabetes and Obesity in Korean Men
Diabetes Care, February 1, 2008; 31(2): 255 - 260.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.