Skip Navigation



IJE Advance Access published online on May 6, 2004
International Journal of Epidemiology, doi:10.1093/ije/dyh077
© 2004 by International Epidemiological Association
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
33/4/779    most recent
dyh077v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Allonier, C.
Right arrow Articles by Lahon, G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Allonier, C.
Right arrow Articles by Lahon, G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Accepted November 19, 2003

Original paper

Anxiety or depressive disorders and risk of ischaemic heart disease among French power company employees

C. Allonier 1, A. Chevalier 1*, M. Zins 2, O. Catelinois 1, S. M. Consoli 3, M. Goldberg 2, G. Lahon 1

1 Service General de Medecine de Contrôle (SGMC), Electricité de France-Gaz de France
2 INSERM U88
3 Department of Psychological Medicine and C-L Psychiatry, Georges Pompidou European Hospital

* To whom correspondence should be addressed. E-mail: anne.chevalier{at}edfgdf.fr.


  Abstract

Background The aim of this study was to determine whether depression and anxiety are predictive factors for ischaemic heart disease among adults <60 years.

Method A case-control study among active employees of the French nationwide power company (Electricité de France--Gaz de France) analysed men aged 31-55 years who presented an initial clinical form of ischaemic heart disease from 1993 through 1997, collected from the company registry. These 660 men were each matched by age to 10 controls per case. Adjusted odds ratios (OR) were calculated by logistic regression.

Results There was a significant association between ischaemic heart disease and sick-leave for any medical reason in the 3 years before its onset (OR = 1.79; 95% CI: 1.50, 2.14). This association was strengthened when only absences for depression and anxiety were considered (OR = 3.10; 95% CI: 2.29, 4.19) and remained important and significant when adjusted for socioeconomic status: OR = 2.66 (95% CI: 1.95, 3.63). A previous sick-leave for depression or anxiety in the 10 years before the heart disease strengthened the association (OR = 3.61; 95% CI: 2.39, 4.45), which was further reinforced by an elevated number (>=4) of such sick-leaves (OR = 5.11; 95 % CI: 3.11, 8.40).

Conclusion Depressive and anxiety disorders that lead to absenteeism seem to be associated with an increased risk of ischaemic heart disease in the 3 years thereafter, especially when depression and anxiety were severe and chronic; this association is independent of socioeconomic status.

Keywords Myocardial infarction, angina pectoris, epidemiology, depressive disorders, socioeconomic status


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.