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IJE Advance Access originally published online on September 17, 2008
International Journal of Epidemiology 2009 38(5):1202-1206; doi:10.1093/ije/dyn192
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.

Cohort Profile: The Danish HIV Cohort Study

Niels Obel1,*, Frederik N Engsig1, Line D Rasmussen2, Mette V Larsen3, Lars H Omland1 and Henrik T Sørensen4,5

1 Department of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet, Denmark.
2 Depertment of Infectious Diseases, Odense University Hospital, Odense, Denmark.
3 Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.
4 Department of Clinical Epidemiology, Aarhus University Hospital, Denmark.
5 Department of Epidemiology, Boston University, Boston, MA, USA.

* Corresponding author. Department of Infectious Diseases, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen Ø, Denmark. E-mail: niels.obel@rh.regionh.dk

Accepted 18 August 2008

The first 150 words of the full text of this article appear below.


   How did the study come about?
 
Shortly after AIDS was recognized in USA, the first cases were diagnosed in Denmark.1,2 Today Denmark has a population of 5.3 million citizens and the prevalence of HIV infection in the adult population is estimated at ~0.07%.3,4 Denmark's HIV epidemic is characterized by the ‘western world pattern’ in which the main transmission routes in the 1980s were between men who had sex with men (MSM), with later spread to heterosexual groups. Since 1995 mortality in the Danish HIV population has fallen drastically as a consequence of highly active antiretroviral therapy (HAART), followed by an increase in HIV prevalence.5 HIV incidence has been rather stable. Denmark's tax-funded health care system provides treatment, including antiretroviral therapy, free-of-charge to all HIV-positive residents. The treatment of HIV-infected patients occurs only in eight specialized medical centres.

Due to the nature of the epidemic and the challenges of modern antiretroviral treatment (e.g. HAART effectiveness, drug toxicity, . . . [Full Text of this Article]


   Who set up DHSC and why, and how was it funded?
 

   What does the cohort cover?
 

   What were the original research topics?
 

   Who is in the sample?
 

   How often have they been followed up?
 

   What has been measured?
 

   What is attrition like?
 

   What has it found?
 

   What are the main strengths and weaknesses?
 

   Can I get hold of the data? Where can I find out more?
 

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