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International Journal of Epidemiology 2008 37(2):379-381; doi:10.1093/ije/dyn036
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.
The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org

Commentary: Calculations of EPIC proportions

Donna Spiegelman*

*Department of Epidemiology and Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA. E-mail: stdls@channing.harvard.edu

Accepted 5 February 2008

The first 150 words of the full text of this article appear below.

Rosner et al.1 developed the necessary methods for the correction of bias due to measurement error in multivariate models in 1990. Although originally focussed on relative risk estimation and inference from logistic regression models, their method was extended in a completely straightforward manner to the Cox model for survival data analysis in a rare disease setting,2,3 as occurs in prospective studies of cancer incidence including the European Prospective Investigation into Cancer and Nutrition (EPIC) study,4 in the Pooling Project of Prospective Studies of Diet and Cancer in Men and Women5 and elsewhere. Smith-Warner and colleagues have successfully applied this method to numerous investigations from the Pooling Project of Prospective Studies of Diet and Cancer in Men and Women.6–11 In this commentary, we will explore how the methods presented in Ferrari et al.'s12 paper differ from Rosner, Spiegelman and Willett's,1,2 and, where differences are apparent, what are the advantages and . . . [Full Text of this Article]


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