IJE Advance Access originally published online on February 14, 2008
International Journal of Epidemiology 2008 37(2):341-343; doi:10.1093/ije/dyn024
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.
Commentary: Epidemiological research on extremely low frequency magnetic fields and Alzheimer's disease—biased or informative?
Institute of Social and Preventive Medicine, University of Bern, Switzerland. E-mail: roeoesli@ispm.unibe.ch
Accepted 14 January 2008
| The first 10% of the full text of this article appears below. |
In 2006 the worldwide prevalence of Alzheimer's disease was estimated to be 26.6 million; and by 2050, Alzheimer's disease prevalence is expected to quadruple because of the increasing life expectancy in many countries.1 Although the years of life lost per Alzheimer's disease case are relatively small, the disease causes considerable distress for afflicted families. Moreover, Alzheimer's disease patients need substantial care resulting in substantial costs for the health care system.
Little is known about the causes of Alzheimer's disease. Several genetic mutations have been identified to be associated with early-onset as well as late-onset disease.2 In addition, environmental factors are assumed to play an important role, particularly for the development of late-onset Alzheimer's disease.3 Many environmental, occupational or lifestyle