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IJE Advance Access originally published online on April 30, 2007
International Journal of Epidemiology 2007 36(2):420-421; doi:10.1093/ije/dym030
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2007; all rights reserved.

Commentary: On the clinical prediction of pre-eclampsia and its enigmatic aetiology

Lorentz M Irgens

Medical Birth Registry of Norway, Locus of Registry Based Epidemiology, Institute of Community Medicine and Primary Health Care, University of Bergen and Norwegian Institute of Public Health, Norway.

E-mail: Lorentz.irgens@fhi.no

Accepted 8 February 2007

The first 10% of the full text of this article appears below.

Even if pre-eclampsia has been considered a nosological entity way back in the history of medicine, its main diagnostic criteria, proteinuria and hypertension, were ascertained only during the last two centuries, proteinuria around 1840 and hypertension in the first decades of the 20th century. However, its aetiology and pathogenesis still represent enigmas and challenges to everyone engaged in perinatal health problems. Issues needing clarification comprise the clinical prediction of pre-eclampsia and its long-term consequences. The increasing evidence . . . [Full Text of this Article]


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