IJE Advance Access originally published online on January 4, 2006
International Journal of Epidemiology 2006 35(1):179-180; doi:10.1093/ije/dyi302
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2006; all rights reserved.
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Commentary: BMI and mortality in the elderlya life course perspective
MRC National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free & University College Medical School, 1-19 Torrington Place, London WC1E 6BT, UK
* Corresponding author. E-mail: r.hardy@nshd.mrc.ac.uk
| The first 10% of the full text of this article appears below. |
The prevalence of obesity is increasing among all ages, including the elderly.1 There is debate about the harm of obesity in the elderly, the relation between obesity in old age and mortality, its clinical relevance, and the need for treatment.2 Studies of the relationship between BMI and mortality have been conflicting and are hampered by reverse causality, healthy survivor effects, and lack of adjustment for confounders such as smoking and physical activity. Research needs to address whether the relationship between BMI and mortality in the elderly is modified by the BMI trajectory before old age or by lifetime changes in body composition (since fat to lean mass ratio increases with age3), and varies by cause of death. A paper in this
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