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IJE Advance Access originally published online on January 19, 2005
International Journal of Epidemiology 2005 34(2):403-404; doi:10.1093/ije/dyi004
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2005; all rights reserved.

Commentary

Commentary: Liver cancer and the epidemiological and cancer transition theories

Omer Gersten

Department of Demography, University of California, Berkeley, 2232 Piedmont Avenue, Berkeley, CA 94720-2120, USA. E-mail: omer@demog.berkeley.edu

The first 10% of the full text of this article appears below.

The article by Shibuya and Yano1 in this issue investigates the most common form of liver cancer in Japan, hepatocellular carcinoma (HCC). Using log-linear Poisson regression models and addressing the problem of non-identifiability, the authors attempt to tease out the influence of age, period, and cohort effects on HCC mortality. An important conclusion of the article is that HCC death rates are highest in cohorts born around 1930. Another conclusion at the opposite end of the spectrum also deserves to be stressed. That is, the lowest levels of HCC belong to the most recent cohorts. Hepatitis is . . . [Full Text of this Article]


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