IJE Advance Access originally published online on May 20, 2004
International Journal of Epidemiology 2004 33(4):858-863; doi:10.1093/ije/dyh116
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
IJE vol.33 no.4 © International Epidemiological Association 2004; all rights reserved.
Height and risk of severe pre-eclampsia. A study within the Danish National Birth Cohort
1 Danish Epidemiology Science Centre, Aarhus, Denmark
2 Epidemiology Branch, 3 Biostatistics Branch, NIEHS (National Institutes of Health), Research Triangle Park, NC, USA
Correspondence: Olga Basso, Danish Epidemiology Science Centre, Department of Epidemiology and Social Medicine, Vennelyst Boulevard 6, Building 260, Aarhus University, 8000 Aarhus C, Denmark. E-mail: ob{at}soci.au.dk
Background Pre-eclampsia shares a number of risk factors with cardiovascular disease (CVD). Women with recurrent pre-eclampsia or pre-eclampsia early in pregnancy reportedly have an increased long-term risk of CVD. Short stature is a risk factor for CVD but has rarely been examined in relation to pre-eclampsia.
Methods We used data from 59 968 singleton live births in the Danish National Birth Cohort born between 1998 and 2001 to assess risk of severe pre-eclampsia/eclampsia (296 cases) in relation to self-reported height. We examined the association in multiple logistic regressions stratified by parity.
Results Among primiparas there was a weak association (compared with women <165 cm, women >172 cm had on OR of 0.79, 95% CI: 0.55, 1.14). Among multiparas, the tallest women had an adjusted OR of 0.42 (95% CI: 0.20, 0.87) of developing severe pre-eclampsia compared with women <165 cm. The OR per centimetre was 0.94 (95% CI: 0.91, 0.97). Self-reported pre-existing hypertension did not explain this association, which also persisted when the analysis was restricted to non-overweight women.
Conclusions Short stature was associated with a higher risk of severe pre-eclampsia in multiparas participating in the Danish National Birth Cohort.
Keywords Height, pregnancy complications, pre-eclampsia (severe), cohort study
Accepted 8 January 2004
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  J. Waden, C. Forsblom, L. M. Thorn, M. Saraheimo, M. Rosengard-Barlund, O. Heikkila, K. Hietala, K. Ong, N. Wareham, P.-H. Groop, et al. Adult Stature and Diabetes Complications in Patients With Type 1 Diabetes: The FinnDiane Study and the Diabetes Control and Complications Trial Diabetes, August 1, 2009; 58(8): 1914 - 1920. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. K. Klemmensen, S. F. Olsen, M. L. Osterdal, and A. Tabor Validity of Preeclampsia-related Diagnoses Recorded in a National Hospital Registry and in a Postpartum Interview of the Women Am. J. Epidemiol., July 15, 2007; 166(2): 117 - 124. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M Catov, R. B Ness, K. E Kip, and J. Olsen Risk of early or severe preeclampsia related to pre-existing conditions Int. J. Epidemiol., April 1, 2007; 36(2): 412 - 419. [Abstract] [Full Text] [PDF]
|
|