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IJE Advance Access originally published online on March 11, 2004
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International Journal of Epidemiology, Volume 33, Number 3, pp. 564-565
IJE vol.33 no.3 © International Epidemiological Association 2004; all rights reserved.

Article

Commentary: Use of antibiotics and risk of asthma

Juha Pekkanen

Unit of Environmental Epidemiology, National Public Health Institute, Kuopio, Finland. E-mail: juha.pekkanen@ktl.fi

The first 10% of the full text of this article appears below.

According to the hygiene hypothesis, infections in early life protect from atopy and asthma.1 Therefore, antibiotics have been hypothesized to cause increased risk of asthma by reducing the protective effect of infections or by interfering with normal gut flora.2 There are, however, several caveats in studying the association between antibiotic use and risk of asthma at the individual level, so the ecological study by Foliaki et al.3 is a welcome addition to the literature.

The possibility of ‘reverse . . . [Full Text of this Article]


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