International Journal of Epidemiology, Volume 33, Number 2, pp. 365-366
IJE vol.33 no.2 © International Epidemiological Association 2004; all rights reserved.
Commentary |
Commentary: Is pertussis disease increasing?
Division of Infectious Disease, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville TN, USA
Correspondence: Kathryn M Edwards, CCC-5323 Medical Center North, Vanderbilt University School of Medicine, Nashville, TN 372322581, USA. E-mail Kathryn.edwards{at}vanderbilt.edu
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Over the past two decades, several countries have reported increasing rates of pertussis disease. In the 1980s the UK and Japan documented increased pertussis illness associated with the decreased uptake of the reactogenic whole-cell pertussis vaccine.1 In the 1990s Canadian epidemiologists reported increased pertussis cases resulting from the administration of an ineffective whole-cell vaccine.2 In the past several years investigators in the US and France have suggested that