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International Journal of Epidemiology, Volume 33, Number 1, pp. 215-216
IJE vol.33 no.1 © International Epidemiological Association 2004; all rights reserved.

Respiratory Disease

Commentary: Nitrogen dioxide and asthma redux

Jonathan M Samet1 and Michelle L Bell1

1 Johns Hopkins Bloomberg School of Public Health, Department of Epidemiology, Baltimore, Maryland USA.

Correspondence: Jonathan M Samet, 615. North Wolfe Street, Rm W6041, Baltimore, Maryland 21205 USA. E-mail: jsamet@jhsph.edu

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Nitrogen dioxide (NO2), a combustion-generated oxidant gas, is widely present in indoor and outdoor environments. Outdoors, where it comes primarily from combustion engines, industry, and power generation, it is a precursor to particles and ozone. Indoors, NO2 is generated by gas cooking and heating, and it exists as a gas along with other oxides of nitrogen. Many epidemiological studies have examined effects of NO2 outdoors and indoors on risk for lower respiratory infection, asthma, and other respiratory diseases and conditions. Evidence from studies of outdoor air . . . [Full Text of this Article]


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