International Journal of Epidemiology 2003;32:1062-1063
© International Epidemiological Association 2003
Theory and Methods |
Commentary: An OPEN assessment of dietary measurement errors
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In epidemiological studies of chronic disease risk in relation to diet, a crucial question is whether assessments of dietary intake can accurately characterize an individuals habitual intake of foods and nutrients. Over the last two decades, this question has been addressed in numerous validation studies. The OPEN study1 provides the best answer yet. It is a true landmark study both because of its size and the thoroughness of its design.
The main innovation of the OPEN study is the use of doubly labelled water (i.e. water made from stable isotopes of both hydrogen and oxygen) to measure energy expenditure. Doubly labelled water is extremely
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