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International Journal of Epidemiology 2003;32:828
© International Epidemiological Association 2003

Infection

Commentary: A hypothesis concerning vitamin A supplementation, vaccines, and childhood mortality

Charles B Stephensen

USDA Western Human Nutrition Research Center, and Nutrition Department, University of California, Davis, CA 95616–8669, USA. E-mail: cstephensen@ucdavis.edu

The first 10% of the full text of this article appears below.

Vitamin A supplements in community intervention trials seem to provide maximum protection against death from infectious diseases when provided at birth or after 6 months of age.1 Why this is so is not clear and part of the reason may be a lack of data in young infants. However, Benn and colleagues2 have other ideas and have proposed a hypothesis to explain this inconsistency. First, a little background information is in order.

The goals of vitamin A supplementation programmes in areas of the world where vitamin A deficiency is a public health problem are, of course, to treat and prevent vitamin A deficiency. . . . [Full Text of this Article]


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