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International Journal of Epidemiology 2003;32:314-315
© International Epidemiological Association 2003

Theory and Methods

Commentary: Black and white or shades of grey?

Markus Battaglia and Daniel Pewsner

Division of Epidemiology and Biostatistics, Department of Social and Preventive Medicine, University of Bern, Finkenhubelweg 11, CH-3012 Bern, Switzerland. E-mail: battag@ispm.unibe.ch

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In the quest for diagnostic certainty we should welcome anything that improves our ability to interpret diagnostic tests. In this issue of the International Journal of Epidemiology Joël Coste and Jacques Pouchot1 describe a method for constructing a three-zone division for continuously measured diagnostic test results. The concept of three-zone diagnostic decision making, coined by Feinstein in 1990,2 strengthens the explanatory power of our customary ‘yes–no’ reasoning by including a grey zone of intermediate values in which a disease cannot be said . . . [Full Text of this Article]


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