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International Journal of Epidemiology 2003;32:294-295
© International Epidemiological Association 2003

Infectious Diseases

Commentary: Infectious diseases during infancy and mortality in later life

G Doblhammer

Max Planck Institute for Demographic Research, Konrad-Zuse Str. 1, 18055 Rostock, Germany. E-mail: doblhammer@demogr.mpg.de

The first 10% of the full text of this article appears below.

Do the very first years of life determine old-age mortality? This question has stimulated an extensive debate since 1973, when Forsdahl published his first paper1 about the effect of very poor living conditions in childhood and adolescence on adult mortality. Further work by Barker and colleagues led to the formulation of the ‘fetal-origins’ hypothesis, which states that chronic disease later in life is caused by nutritional deficiencies in utero.2 While these theories are developed on the basis of studies of mortality in the 20th century, Fridlizius3 suggested that, in the 19th century, exposure to infectious disease in the first 5 years . . . [Full Text of this Article]


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