International Journal of Epidemiology 2003;32:116-117
© International Epidemiological Association 2003
Infectious Diseases |
Commentary: Non-specific effects of measles vaccinemore grist for the mill
Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, UK.
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This paper1 represents another in a series of publications by Peter Aaby and colleagues on unexpected and non-specific effects of vaccines. For several years, these authors have argued in particular that the benefits of measles vaccines are greater than that which can be explained by protection against measles virus. This time they re-analyse data from an evaluation of measles vaccine carried out in the early 1980s in the Matlab demographic surveillance population associated with the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), comparing mortality between areas in which Schwarz strain measles vaccine was (areas A and C) and was not (areas B and D) offered to children between 9 and 60 months of age: 8134 vaccinated children