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International Journal of Epidemiology 2003;32:116-117
© International Epidemiological Association 2003


Infectious Diseases

Commentary: Non-specific effects of measles vaccine—more grist for the mill

Paul EM Fine

Department of Infectious and Tropical Disease, London School of Hygiene and Tropical Medicine, London, UK.

The first 10% of the full text of this article appears below.

This paper1 represents another in a series of publications by Peter Aaby and colleagues on unexpected and ‘non-specific’ effects of vaccines. For several years, these authors have argued in particular that the benefits of measles vaccines are greater than that which can be explained by protection against measles virus. This time they re-analyse data from an evaluation of measles vaccine carried out in the early 1980s in the Matlab demographic surveillance population associated with the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), comparing mortality between areas in which Schwarz strain measles vaccine was (areas A and C) and was not (areas B and D) offered to children between 9 and 60 months of age: 8134 vaccinated children . . . [Full Text of this Article]


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