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International Journal of Epidemiology 2002;31:646-647
© International Epidemiological Association 2002

Infectious Diseases

Commentary: What remains to be done regarding transmission of Helicobacter pylori

David Y Graham and Hoda M Malaty

Department of Medicine, VA Medical Center and Baylor College of Medicine, Houston, Texas, USA.

David Y Graham, Rm 3A-320 (111D), Veterans Affairs Medical Center, 2002 Holcombe Blvd., Houston, Texas 77030, USA. E-mail: dgraham@bcm.tmc.edu


   Introduction
 
Helicobacter pylori causes a chronic and serious infection. Helicobacter pylori shares with syphilis and tuberculosis the features of a long latent period, a small proportion of infected individuals experiencing clinical illness, and a male predominance of clinical disease despite equal infection among sexes. Humans are the only known reservoir. Transmission is ‘opportunistic’ in that any method that allows the organism access to the stomach is likely to be a mode of transmission. The most common modes of transmission involve lapses in household hygiene, or ingestion of contaminated food or water. The infection is typically acquired in childhood or when children . . . [Full Text of this Article]


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