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International Journal of Epidemiology 2001;30:1279-1280
© International Epidemiological Association 2001

Perinatal epidemiology

Commentary: Mercury, PCB, and now eicosapentaenoic acid: still another reason why pregnant women should be concerned about eating seafood?

Sjúr{partial}ur F Olsen

Maternal Nutrition Group, Danish Epidemiology Science Centre, Statens Serum Institut, 5 Artillerivej, DK-2300 Copenhagen S, Denmark. E-mail: sfo@ssi.dk

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are collectively described as marine fatty acids since they derive mainly from marine food sources. They are believed to protect against cardiovascular diseases and perhaps also prostate cancer and rheumatoid arthritis. With regard to pregnancy and the perinatal period, there is evidence from randomized controlled trials that they may have the potential to prevent preterm birth, and DHA is known to be essential to early neurodevelopment.

In a paper in this issue Grandjean et al.1 conclude that consumption of relatively high amounts of EPA in pregnancy may have a negative impact on fetal growth. The study is based on 179 pregnancies in the Faroe Islands. Maternal samples taken in gestation week 34 were analysed for fatty acids in serum and PCB compounds (a group of organochlorines) and mercury in whole blood, whereas umbilical samples were . . . [Full Text of this Article]

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