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International Journal of Epidemiology 2001;30:465-466
© International Epidemiological Association 2001

Child Health in Africa

Commentary: Is vitamin A playing a hidden role in children's lung function?

Fernando Sempértegui

Corporación Ecuatoriana de Biotecnología, Department of Immunology, Universidad Central del Ecuador, Escuela de Medicina, Av. Colón, 1485 y nueve de Octubre, of. 202, Quito, Ecuador.

Kassaye et al.1 have evaluated for the first time the relationship between vitamin A status and respiratory function in children. Previous studies in adults suffering from chronic diseases, which affect respiratory function, have shown a beneficial effect of short-term vitamin A supplementation on forced expiratory volume (FEV1) and/or forced vital capacity (FVC). Because vitamin A deficiency is associated with keratinizing metaplasia of the respiratory tract in children, the authors hypothesized that the differential vitamin A status of malnourished children could be related . . . [Full Text of this Article]

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F. D. Gilliland, K. T. Berhane, Y.-F. Li, W. J. Gauderman, R. McConnell, and J. Peters
Children's Lung Function and Antioxidant Vitamin, Fruit, Juice, and Vegetable Intake
Am. J. Epidemiol., September 15, 2003; 158(6): 576 - 584.
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