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International Journal of Epidemiology 2001;30:285-297
© International Epidemiological Association 2001


Special Theme: Socioeconomic Differentials in Health

Time trends of major coronary risk factors in a northern Italian population (1986–1994). How remarkable are socioeconomic differences in an industrialized low CHD incidence country?

Marco Ferrarioa, Roberto Segaa, Liliana Chatenoudb, Giuseppe Manciaa, Paolo Mocarellic, Carla Crespic, Giancarlo Cesanaa and for the MONICA–Brianza Research Group

a Research Centre for Chronic Degenerative Diseases and Department of Internal Medicine and Prevention and Health Biotechnology, University of Milan–Bicocca, Milan, Italy.
b Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
c Department of Laboratory Medicine at Hospital of Desio, University of Milan–Bicocca, Milan, Italy.

Correspondence to: Marco Ferrario, Centro Ricerche Patologia Cronico-Degenerativa; Università degli Studi di Milano–Bicocca; Ospedale San Gerardo, Villa Serena–VI piano; Via Donizetti, 106; 20052 Monza (MI), Italy. E-mail: marco.ferrario{at}unimib.it

Abstract

Background The goals are to estimate time trends (1986–1994) of major coronary risk factors in an industrialized low CHD incidence population and to assess education class (EC) differences in risk factor prevalence and in time trends.

Methods Three population surveys were conducted in 1986–1987, 1989–1990 and 1993– 1994 on independent and two-stage age- and gender-stratified random samples (1906 men and 1941 women) of 35–64 year old residents of Brianza, an affluent region of northern Italy. The protocol for data collection, clinical measurements and biochemical determinations adhered to the WHO MONICA manual and underwent repeated quality control assessments. EC were identified according to gender- and 5-year birth-cohort specific tertiles.

Results In the initial, middle and final surveys 1258, 1259 and 1330 subjects were enrolled, corresponding to participation rates of 70.1%, 70.3% and 74.3%, respectively. Over the 8-year period, in men systolic blood pressure and smoking habits declined, body mass index and serum total cholesterol increased. In women systolic blood pressure showed a constant reduction, total cholesterol and BMI increased and the prevalence of smokers remained stable. Overall inverse associations with EC were found for body mass index, for prevalence of cigarette smokers in men and for systolic blood pressure in women. Decreases in blood pressure were more evident in the lowest EC. Cigarette smoking was on the decline in the higher EC in men. BMI and total cholesterol increased in all EC with the notable exception of the ‘low’ EC in women.

Conclusions Favourable changes of the risk factor profile in the low socio-economic classes may have contributed to reduce CHD rates in this population. Specific policies oriented to lowest socio-economic classes are needed to continue to combat the smoking epidemic.

Keywords Coronary risk factors, trends, socio-economic status, Italy

Accepted 12 December 2000


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