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International Journal of Epidemiology 2001;30:57-59
© International Epidemiological Association 2001


Special Theme: Fetal Origins of Health and Disease

Commentary: Fetal origins of cardiovascular risk—nutritional and non-nutritional

CS Yajnik

Diabetes Unit, King Edward Memorial Hospital Research Centre, Rasta Peth, Pune 411011, India.

A paper in this issue of the IJE adds to the already long list of papers which show an association between small size at birth and cardiovascular risk in later life. Barker's idea of the ‘fetal origins’1 has survived and strengthened through the last decade, albeit undergoing a degree of metamorphosis to include contributions from childhood growth.2

The multicentre study3 confirms the relationship of small size at birth with blood pressure in young children from three developing countries (China, Guatemala and Chile). There . . . [Full Text of this Article]

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