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International Journal of Epidemiology 2001;30:152-153
© International Epidemiological Association 2001

Cardiovascular Disease

Commentary: Lung function and risk of fatal and non-fatal stroke—The Copenhagen City Heart Study

Lindsey Dowa and Shah Ebrahimb

a Department of Health Care of the Elderly and
b Department of Social Medicine, University of Bristol, Bristol, UK.

Prof. Shah Ebrahim, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK. E-mail: shah.ebrahim@bristol.ac.uk

The findings of Truelsen and colleagues1 confirm earlier reports of the inverse association of lung function with risk of both fatal and non-fatal stroke.2,3 Is a link between markers of abnormal vascular biology and airway function surprising? The relationship is attenuated when adjustment is made for other potential confounders, particularly age, sex and smoking. This shows that much of the relationship is explained by these factors. While there remains a possibility that residual confounding, due to imprecise measurement of lifetime tobacco exposure, is a sufficient explanation for the findings, among those who have . . . [Full Text of this Article]

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