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International Journal of Epidemiology, Vol 28, 509-513, Copyright © 1999 by International Epidemiological Association


ARTICLES

Prevalence and correlates of anergy among drug users in Puerto Rico

RR Robles, JC Reyes, HM Colon, TD Matos, L Vila Perez and CA Marrero
Center for Addiction Studies, Universidad Central del Caribe, Bayamon, Puerto Rico 00960-6032.

OBJECTIVES: This study assessed prevalence and correlates of anergy among a cohort of drug users in communities in the San Juan metropolitan area. METHODS: In all, 719 drug injectors and crack users were recruited in neighbourhoods in the San Juan metropolitan area following a stratified cluster design of 30 copping areas (places where drugs are sold). RESULTS: Slightly more than one-third of the total proportion of participants, 34.2%, were HIV positive and 30.3% anergic. Subjects with a history of incarceration, the HIV positive, and those reporting chronic illness were more likely to be anergic than those subjects without these characteristics. CONCLUSIONS: Most studies addressing drug users' immune system dysfunction are related to HIV infection. Additional studies are needed to provide a more comprehensive understanding of drug users' immune systems.
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