International Journal of Epidemiology, Vol 28, 211-218, Copyright © 1999 by International Epidemiological Association
M Kirchhoff, M Davidsen, H Bronnum-Hansen, B Hansen, H Schnack, LS Eriksen, M Madsen and M Schroll
BACKGROUND: Cardiovascular mortality has been declining in Denmark over the
past 20 years. Trends in incidence of myocardial infarction (MI) over the
period 1982-1991 are described within the framework of the World Health
Organization MONICA Project. METHODS: The DAN-MONICA heart register
included all cases of MI in 25-74-year-old men and women living in 11
municipalities around Glostrup County Hospital evolving over a period of 10
years. They were identified retrospectively based mainly on relevant ICD
diagnoses in death certificates and hospital discharge reports. Cases
meeting WHO-MONICA criteria for definite or possible MI, recurrent as well
as first-ever MI, were registered. Subsequent tracing of cases through
national registers on deaths and hospitalizations by means of the patient's
civil registration number ensured the completeness of the registration.
RESULTS: A total of 6025 cases of MI occurred in the period, 4532 among men
and 1493 among women. A total of 2923 men and 1047 women had a first-ever
MI in the period. The age-standardized rates show a definite decline over
the registration period for men and a less distinct decline for women.
CONCLUSIONS: The DAN-MONICA heart register meets the requirements for
completeness and uniformity throughout the registration period. Causes and
magnitude of bias are well described. Even when possible sources of bias
are taken into account, the incidence of MI decreased significantly over
the 10-year-period 1982-1991 by an average of 5.0% per year for men and
3.5% per year for women.
ARTICLES
Incidence of myocardial infarction in the Danish MONICA population 1982- 1991
Department of Medicine C, Glostrup Hospital, University of Copenhagen, Denmark.
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