International Journal of Epidemiology, Vol 26, 873-879, Copyright © 1997 by International Epidemiological Association
S Conti, M Masocco, G Farchi, G Rezza and V Toccaceli
BACKGROUND: AIDS has become a leading cause of premature mortality in many
countries, owing to the decline in other major causes of premature death
and the increase in AIDS itself. This study was carried out to determine
the trends in premature mortality due to selected causes in Italy. METHODS:
Data from the Italian Mortality Data Base, for the ten years from 1984 to
1993 (the first decade of the AIDS epidemic) were analysed. Premature
mortality was measured in terms of years of potential life lost before the
age of 70 years (YPLL), excluding infant mortality. Trends in premature
mortality due to AIDS were compared with those of the principal causes of
premature death: lung cancer, colon- rectum cancer, stomach cancer,
leukaemia, female breast cancer, uterine cancer, myocardial infarction,
stroke, liver diseases, suicide, road accidents and overdose. RESULTS: In
this period there has been a marked increase in premature mortality from
AIDS both among males aged 1-69 years (from a rate of YPLL of 0.01 per 1000
in 1984 to 3.71 in 1993) and females of the same age group (from 0 deaths
in 1984 to a rate of YPLL of 1.02). Throughout the same period all the
other causes of premature death have been declining, with the exception of
suicide and overdose among males, and overdose and lung cancer among
females. For people aged 25-44 years, AIDS has become the greatest cause of
premature death. The increasing trend in premature mortality due to AIDS is
most pronounced in the northern and central areas of Italy. CONCLUSIONS:
AIDS is the leading cause of death among males aged 25-44 years in Italy
and is having an important impact on premature mortality among females in
the same age group.
ARTICLES
Premature mortality in Italy during the first decade of the AIDS epidemic: 1984-1993
Laboratory of Epidemiology and Biostatistics, Istituto Superiore di Sanita, Rome, Italy.
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