International Journal of Epidemiology, Vol 26, 224-227, Copyright © 1997 by International Epidemiological Association
CG Victora, SR Huttly, SC Fuchs and MT Olinto
BACKGROUND: This paper discusses appropriate strategies for multivariate
data analysis in epidemiological studies. METHODS: In studies where
determinants of disease are sought, it is suggested that the complex
hierarchical inter-relationships between these determinants are best
managed through the use of conceptual frameworks. Failure to take these
aspects into consideration is common in the epidemiological literature and
leads to underestimation of the effects of distal determinants. RESULTS: An
example of this analytical approach, which is not based purely on
statistical associations, is given for assessing determinants of mortality
due to diarrhoea in children. CONCLUSIONS: Conceptual frameworks provide
guidance for the use of multivariate techniques and aid the interpretation
of their results in the light of social and biological knowledge.
ARTICLES
The role of conceptual frameworks in epidemiological analysis: a hierarchical approach
Universidade Federal de Pelotas, CP, RS, Brasil.
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