Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (43)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by PARAZZINI, F.
Right arrow Articles by ACAIA, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by PARAZZINI, F.
Right arrow Articles by ACAIA, B.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1991 Oxford University Press

research-article

Risk Factors for Spontaneous Abortion

FABIO PARAZZINI*,*, LUCA BOCCIOLONE*,**, LUIGI FEDELE**, EVA NEGRI*, CARLO LA VECCHIA*,{dagger} and BARBARA ACAIA**

*Istituto di Ricerche Farmacologiche ‘Mario Negri’ Via Entrea 62, 20157 Milano, Italy.
**Prima Clinica Ostetrico-Ginecologica, Universitŕ di Milano 20122 Milano, Italy.
{dagger}Institut universitaire de médicine sociale et préventive 1005, Lausanne, Switzerland.

Correspondence to: Fabio Parazzini, Istituto di Ricerche Farmacologiche ‘Mario Negri’. Via Eritrea 62, 20157 Milano, Italy.

A case-control study was conducted to evaluate risk factors for spontaneous abortions. Cases were 94 women with two or more unexplained miscarriages (after exclusion of genetic, endocrine and Müllerian factors) and no term pregnancy, controls were 176 women admitted for normal delivery to the same clinic where cases were identified. Questions were asked about personal characteristics and habits, and gynaecological history. A family history of recurrent miscarriage was more common among women with spontaneous miscarriages than among the controls (13 cases versus 8 controls, relative risk (RR) =3.2, 95% confidence interval (CI) = 1.3–8.1). Compared to women whose menarche occurred at age 11 or younger, the RRs were 0.8 when menarche occurred at age 12–13 and 0.5 at age 14 or more: this trend in risk was statistically significant. Compared with never smokers, current smokers had about a 40% increased risk of miscarriage and the risk increased with number of cigarettes per day. No association emerged with socio-demographic characteristics (e.g. education, marital status, age of the partner), reproductive history (age at first pregnancy), type of contraceptive used and other general lifestyle habits (e.g. alcohol or coffee consumption).

Revised 1 August 1990


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am J EpidemiolHome page
B. H. Bech, E. A. Nohr, M. Vaeth, T. B. Henriksen, and J. Olsen
Coffee and Fetal Death: A Cohort Study with Prospective Data
Am. J. Epidemiol., November 15, 2005; 162(10): 983 - 990.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
F. Sata, H. Yamada, K. Suzuki, Y. Saijo, E. H Kato, M. Morikawa, H. Minakami, and R. Kishi
Caffeine intake, CYP1A2 polymorphism and the risk of recurrent pregnancy loss
Mol. Hum. Reprod., May 1, 2005; 11(5): 357 - 360.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
Y. Saijo, F. Sata, H. Yamada, K. Suzuki, S. Sasaki, T. Kondo, Y.Y. Gong, E.H. Kato, S. Shimada, M. Morikawa, et al.
Ah receptor, CYP1A1, CYP1A2 and CYP1B1 gene polymorphisms are not involved in the risk of recurrent pregnancy loss
Mol. Hum. Reprod., October 1, 2004; 10(10): 729 - 733.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
F. Sata, H. Yamada, A. Yamada, E. H. Kato, S. Kataoka, Y. Saijo, T. Kondo, J. Tamaki, H. Minakami, and R. Kishi
A polymorphism in the CYP17 gene relates to the risk of recurrent pregnancy loss
Mol. Hum. Reprod., November 1, 2003; 9(11): 725 - 728.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
F. Sata, H. Yamada, T. Kondo, Y. Gong, S. Tozaki, G. Kobashi, E.H. Kato, S. Fujimoto, and R. Kishi
Glutathione S-transferase M1 and T1 polymorphisms and the risk of recurrent pregnancy loss
Mol. Hum. Reprod., March 1, 2003; 9(3): 165 - 169.
[Abstract] [Full Text] [PDF]

Home page
 NeurologyHome page
N. Schupf and R. Ottman
Risk of epilepsy in offspring of affected women: Association with maternal spontaneous abortion
Neurology, November 13, 2001; 57(9): 1642 - 1649.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
P.-Y. Ancel, M.-J. Saurel-Cubizolles, G. C. Di Renzo, E. Papiernik, G. Breart, and T. Europop Group
Risk factors for 14-21 week abortions: a case-control study in Europe
Hum. Reprod., November 1, 2000; 15(11): 2426 - 2432.
[Abstract] [Full Text] [PDF]

Home page
 The Journal of the Royal Society for the Promotion of HealthHome page
L. A. Al-Ansary and Z. A. Babay
Risk Factors for Spontaneous Abortion: A Preliminary Study on Saudi Women
The Journal of the Royal Society for the Promotion of Health, August 1, 1994; 114(4): 188 - 193.
[Abstract]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.