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© 1990 Oxford University Press

research-article

Endometrial Cancer Trends in England and Wales: A Possible Protective Effect of Oral Contraception

LAURENCE VILLARD and MIKE MURPHY

Department of Community Medicine and Gerneral Practice, University of Oxford Gibson Building, Radcliffe Infirmary, Oxford OX2 6HE, UK.

Villard L (Department of Community Medicine and General Practice, University of Oxford, Gibson Building, Radcliffe Infirmary, Oxford OX2 6HE, UK) and Murphy M. Endometrial cancer trends in England and Wales. A possible protective effect of oral contraceptives. International Journal of Epidemiology 1990, 19: 255–258.

Case-control studies have shown that combined oral contraceptives (OCs) are protective against endometrial cancer. In England and Wales, OCs have been on the market for 30 years and widely used for 20 years. Trends in other known risk factors for endometrial cancer would tend to have increased its incidence in that time in women under 55 years of age. Vital statistics however show a decrease for endometrial cancer mortality (41%) and morbidity (15%) in that group. This suggests an important protective effect of OCs on this disease.

Revised 1 September 1989


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