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© 1983 Oxford University Press

research-article

An Aetiological Evaluation of Increased Occurrence of Congenital Limb Reduction Abnormalities in Hungary, 1975–1978

ANDREW CZEIZEL*, STEFAN KELLER* and MARIA BOD{dagger}

* Department of Human Genetics, National Institute of Hygiene Gyáli ut 2–6, 1966, Budapest, Hungary
{dagger} First Department of Paediatrics, Semmelweis University Medical School Budapest, 1083, Hungary

In Hungary a significant increase occurred in the birth prevalence of congenital limb reduction abnormalities from 1975 to 1978 after the introduction of a new population policy in 1974. A case-control study showed a slight increased use of drugs for ovulation induction, oral contraceptives prior to conception and more frequent extramarital births as well as unwanted pregnancies.

Received 1 December 1982


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