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© 1981 Oxford University Press

research-article

Glucose — 6 — Phosphate Dehydrogenase Deficiency in Çukurova Province, Turkey

T AKOLU,*, FLÖZER,*, S ÇIC**, M KÜMI,*, A ERDOEAN* and H ANIL*

Akoglu T [Çkurova University, Medical Faculty, Department of Haematology, Adana, Turkey], Özer FL, ÇiC S, Kümi M, Erdogan A and Anil H. Glucose-6-phosphate dehydrogenase deficiency in Çukurova province, Turkey. International Journal of Epidemiology, 1981, 10: 27–29.
*Cukurova Üniversity, Medical Faculty, Department of Haematology, Adana, Turkey
** Regional Headquarters of the State Malaria Eradication Organisation, Adana, Turkey This work was supported by a Grant from WHO, TUR-LAB-002/DP/79.

The prevalence of red cell G, PD deficiency was studied by a flourescence screening test in 5 different ethnic populations of Cukurova province. Analyses were performed on samples from the parents of each family unit. The frequency of occurrence in the population was calculated using family trees.4 551 subjects representing 17 225 offspring from 18 villages were screened and a high incidence of G, PD deficiency was found in the Arabic speaking ethnic groups from Adana (10.4%) and Anthiochus regions (8.1%), whereas the deficiency was only 3.1% in Armenians, 0.8% in mixed villages and 0.5% in Turcomans. This study reveals that the high frequency of this deficiency found in some ethnic populations must be taken into account prior to the treatment of malaria with primaquine.

Revised 14 August 1980


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