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© 1972 Oxford University Press

research-article

Continuing Surveillance of Families for Studying the Epidemiology of Viral Infections

JOHN P. FOX1, and CARRIE E. HALL2

1 Department of Epidemiology and International Health, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98105, U.S.A.
2 Department of Epidemiology and International Health, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98105, U.S.A.

Requests for reprints may be addressed to Dr. J. P. Fox

Fox, J. P. (Department of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, U.S.A.), and Hall, C. E. Continuing surveillance of families for studying the epidemiology of viral infections. Int. J. Epid. 1972. 1: 31–37.

This paper reviews 17 years experience in studying the natural history of contact-transmitted viruses by continuing virologic surveillance of families. Although dependent on volunteers, the method permits description of the full spectrum of clinical response to infection and of the patterns of occurrence of infections in free-living populations. The method is particularly useful for the study of agents which can be readily isolated in vitro and which infect with reasonable frequency and it constitutes virtually the only approach to describing the natural history of agents causing infections which are frequently or predominantly inapparent and only rarely result in medically attended disease.


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