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IJE Advance Access originally published online on January 24, 2006
International Journal of Epidemiology 2006 35(2):491; doi:10.1093/ije/dyi313
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2006; all rights reserved.

Letter to the Editor

Maternal smoking during pregnancy and offspring IQ

P N Lee

P.N. Lee Statistics and Computing Ltd, 17 Cedar Road, Sutton, Surrey SM2 5DA, UK

E-mail: PeterLee{at}pnlee.demon.co.uk

Sirs,

Breslau et al.1 report that a strong association between maternal smoking during pregnancy and the IQ of the offspring is eliminated by adjustment for various maternal characteristics. The final model (model 4 in tables 5 and 6) includes low birthweight as one of the characteristics adjusted for. Since maternal smoking during pregnancy may affect the prevalence of low birthweight, inclusion of low birthweight in the model may be regarded as possible over adjustment. It would be interesting to know whether the main conclusion would still remain if adjustment was made only for maternal IQ, education, and urban/rural residence and not for low birthweight.

Conflict of Interest statement: I am a long-term consultant to the tobacco industry.

References

1 Breslau N, Paneth N, Lucia VC, Paneth-Pollak R. Maternal smoking during pregnancy and offspring IQ. Int J Epidemiol 2005;34:1047–53.[Abstract/Free Full Text]


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This Article
Right arrow Extract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
35/2/491    most recent
dyi313v1
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