IJE Advance Access published online on June 15, 2009
International Journal of Epidemiology, doi:10.1093/ije/dyp235
Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2009; all rights reserved.
Commentary: Environmental determinants of dimorphic systemic mycoses—the macro and the micro
1 Department of Family Medicine, University of Wisconsin School of Medicine and Public Health Milwaukee, Wisconsin (WI), USA.
2 Aurora University of Wisconsin Medical Group, Center for Urban Population Health, Milwaukee, Wisconsin (WI), USA. E-mail: dennis.baumgardner@fammed.wisc.edu
Accepted 20 May 2009
| The first 10% of the full text of this article appears below. |
The article by Barrozo et al.1 in this issue is a most interesting investigation of the effect of climatic features on the yearly incidence of paracoccidioidomycosis (PCM), a serious systemic mycosis of Latin America. The epidemiology of PCM is very difficult to study due to the long and unpredictable latency period of the common (adult) form of the disease. The authors have taken care to restrict their analysis to area residents with the uncommon acute form of the disease. The authors discuss the limitations of their study, including the particular concern of the small