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IJE Advance Access published online on May 9, 2008
International Journal of Epidemiology, doi:10.1093/ije/dyn081
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.

Commentary: Disease modelling to inform policy on male circumcision for HIV prevention

Ronald H Gray1,*, Maria J Wawer1, Godfrey Kigozi2 and David Serwadda3

1Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland, USA.
2Rakai Health Sciences Program, Entebbe, Uganda.
3School of Public Health, Makerere University, Kampala, Uganda.

*Corresponding author. E-mail: rgray@jhsph.edu

Accepted 7 April 2008

The first 10% of the full text of this article appears below.

The findings from three randomized trials1–3 and multiple observational studies4 that male circumcision prevents HIV acquisition in men has been welcomed as an historic opportunity to control the HIV epidemic, particularly in sub-Saharan Africa.5 However, the challenges are daunting because we have never attempted to use surgery as a means of controlling an infectious disease, the African health infrastructure is weak and trained personnel required to provide circumcision surgery on a massive scale are limited. Therefore, . . . [Full Text of this Article]


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