IJE Advance Access originally published online on February 8, 2008
International Journal of Epidemiology 2008 37(6):1220-1226; doi:10.1093/ije/dym225
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.
Cohort Profile: The Cardiovascular Risk in Young Finns Study
1 Department of Clinical Physiology, University of Turku, Turku, FIN-20521, Finland.
2 Department of Cardiovascular Research Center, University of Turku, Turku, FIN-20521, Finland.
3 Department of Medicine, University of Turku, Turku, FIN-20521, Finland.
4 Department of Psychology, University of Helsinki, Helsinki, FIN-00014, Finland.
5 Department of Nutrition, University of Helsinki, Finland, Helsinki, FIN-00014, Finland.
6 Center of Social and Health Services, City of Kuopio, Kuopio, FIN-70101, Finland.
7 Department of Pediatrics, University of Tampere, Tampere, FIN-33014, Finland.
8 Department of Pediatrics, University of Oulu and Vaasa Central Hospital, Vaasa, FIN-65130, Finland.
9 Hospital for Children and Adolescents, University of Helsinki, Helsinki, FIN-00014, Finland.
10 Department of Health and Functional Capacity, National Public Health Institute, Turku, FIN-20720, Finland.
11 Department of Physical Education, University of Jyväskylä, Jyväskylä, FIN-20720, Finland.
12 Department of Clinical Physiology, University of Tampere, Tampere, FIN-40014, Finland.
13 Department Clinical Chemistry, University of Tampere, Tampere, FIN-33014, Finland.
* Corresponding author. Department of Clinical Physiology, PO Box 52, 20521 Turku, Finland. E-mail: olli.raitakari@utu.fi
Accepted 16 October 2007
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How did the study come about? |
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In Finland, coronary heart disease (CHD) incidence was very high in the 1960s and 1970s.1 In line with this high incidence, the Seven Countries Study showed that the level of serum cholesterol in Finns was also the highest among the investigated countries in the 1960s.2 Because several studies indicated that the atherosclerotic process starts early in life, and in accord with the World Health Organization Recommendation of 19783 which stated that studies assessing atherosclerosis precursors in children should be initiated, a program was launched in Finland in the late 1970s to study cardiovascular risk in the youth.4–6 The Cardiovascular Risk in Young Finns Study was designed as a collaborative effort between five university departments of medical schools (i.e. in Helsinki, Kuopio, Oulu, Tampere and Turku) and several other institutions in Finland. The aim was to study the levels of CHD risk factors and their determinants in children and adolescents of
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What does it cover? |
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Who is in the sample? |
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How often have they been followed up? |
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What has been measured? |
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Cardiovascular risk factors
Vascular ultrasound studies
DNA banking and genotyping
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What is attrition like? |
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What has it found? Key findings and key publications |
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The 21-year follow-up study
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What are the main strengths and weaknesses? |
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Can I get hold of the data? Where can I find out more? |
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  C. G. Magnussen, A. Venn, R. Thomson, M. Juonala, S. R. Srinivasan, J. S.A. Viikari, G. S. Berenson, T. Dwyer, and O. T. Raitakari The association of pediatric low- and high-density lipoprotein cholesterol dyslipidemia classifications and change in dyslipidemia status with carotid intima-media thickness in adulthood evidence from the cardiovascular risk in Young Finns study, the Bogalusa Heart study, and the CDAH (Childhood Determinants of Adult Health) study. J. Am. Coll. Cardiol., March 10, 2009; 53(10): 860 - 869. [Abstract] [Full Text] [PDF]
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