IJE Advance Access originally published online on August 24, 2008
International Journal of Epidemiology 2008 37(6):1211-1213; doi:10.1093/ije/dyn171
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.
Commentary: Lactose and ischaemic heart disease: a sweet hypothesis ... but nothing more!
Honorary Professor, Department of Primary Care and Public Health, Cardiff University, University Hospital, Cardiff CF14 4YS, UK. E-mail: pelwood@doctors.org.uk
Accepted 30 June 2008
| The first 10% of the full text of this article appears below. |
In 1964 John Yudkin and colleagues1 published a report on sucrose intake by patients with vascular disease and control subjects. The mean sugar intake of the patients was nearly twice as high as that of the control subjects and much of the additional sugar appeared to have been taken in cups of tea and coffee. This focus on sucrose is strangely inconsistent with the far-reaching conclusion drawn in an earlier paper by Yudkin2 that it is difficult to support any theory which supposes a single dietary cause of coronary thrombosis ... (and) it is suggested that relative over-consumption of food associated with reduced physical exercise, may be one of several causes of the disease.
The mention of sucrose, however, stimulated a number of reports. These either refuted the
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