IJE Advance Access originally published online on February 19, 2008
International Journal of Epidemiology 2008 37(4):716-720; doi:10.1093/ije/dyn028
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.
Cohort Profile: The Institute of Nutrition of Central America and Panama (INCAP) Nutrition Trial Cohort Study
1 Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta GA 30322, USA.
2 Instituto de Nutrición de Centro América y Panamá (INCAP), Guatemala City, Guatemala.
3 International Food Policy Research Institute (IFPRI), Washington DC, USA.
* Corresponding author. Hubert Department of Global Health, Emory University, 1518 Clifton Rd., NE, Atlanta GA 30322, USA. E-mail: rmart77@sph.emory.edu
Accepted 22 January 2008
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How did the study come about? |
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In the mid-1960s, protein deficiency was seen as the most important nutritional problem facing the poor in the developing countries, and there was considerable concern that this deficiency affected children's ability to learn. The Institute of Nutrition of Central America and Panama (INCAP), based in Guatemala, became the locus of a series of studies on this subject, that informed the development of a large-scale randomized nutritional intervention trial that ran from 1969 to 1977.1,2 The principal hypothesis underlying the intervention was that improved preschool nutrition would accelerate mental development. An examination of the effects on physical growth was also included to verify that the nutritional intervention had biological potency, which was demonstrated.2 Initially, 300 communities were screened to identify villages of appropriate size, compactness, ethnicity and language, diet, access to health care facilities, demographic characteristics, nutritional status and degree of physical isolation. From this group, two pairs of similar villages
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What is attrition like? |
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