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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2008; all rights reserved.
Commentary: Growth of beanbag genetics
Genetic Epidemiology, Human Genetics Division, School of Medicine, University of Southampton (Mailpoint 808), SO16 6YD, UK. E-mail: nem@soton.ac.uk
Accepted 20 December 2007
| The first 10% of the full text of this article appears below. |
Half a century ago Ernst Mayr expressed a zoologist's antipathy to mathematical theories of genetic variation and evolutionary change.1 He later stigmatized them as beanbag genetics,2 for which the relation between genotype and phenotype is fully specified in terms of a small number of parameters. This prompted a spirited defence from JBS Haldane3 who went beyond Mayr's interest in systematics and the origin of
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