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IJE Advance Access originally published online on May 17, 2007
International Journal of Epidemiology 2007 36(6):1190-1195; doi:10.1093/ije/dym091
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2007; all rights reserved.

Cohort Profile: The Chennai prospective study of mortality among 500 000 adults in Tamil Nadu, South India

Vendhan Gajalakshmi1,2,*, Richard Peto3, Vendhan Chiruvai Kanimozhi1, Gary Whitlock3 and Dasarathi Veeramani1

1 Epidemiological Research Center, Chennai, Tamil Nadu, India.
2 International Agency for Research on Cancer, Lyon, France.
3 Clinical Trial Service Unit & Epidemiological Studies Unit, University of Oxford, UK.

* Corresponding author. E-mail: gajaerc@gmail.com

The first 150 words of the full text of this article appear below.


   How did the study come about?
 
A prospective study of half a million adults living in the city of Chennai (formerly Madras) arose out of discussions at the 1994 International Cancer Congress in Delhi about how to assess the effects of tobacco on health in different parts of India. Chennai is the capital of the South Indian state of Tamil Nadu, and it is India's fourth most populous city. Two large-scale epidemiological studies of tobacco and other factors were established: a case-control study1 that could provide reasonably reliable results quickly, and a prospective cohort study that could provide more robust results over a longer period. (A parallel prospective study of 100 000 adults, not included in this profile, is in progress in the nearby rural area of Villupuram; Figure 1.) The case-control analyses,1 which involved 43 000 adult deaths during 1995–97 and 35 000 controls who had been living with a case, indicated that smoking . . . [Full Text of this Article]


   What does it cover?
 

   Who is in the sample?
 
How often are they being followed-up?

   What has been measured?
 

   What is attrition like?
 

   What has it found?
 

   What are the main strengths and weaknesses?
 

   Where can I find out more?
 

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