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IJE Advance Access originally published online on April 23, 2007
International Journal of Epidemiology 2007 36(2):287-289; doi:10.1093/ije/dym056
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2007; all rights reserved.

Commentary: The ubiquity of prostate cancer: echoes of the past, implications for the present

"What has been will be again, what has been done will be done again,; there is nothing new under the sun." ECCLESIASTES 1:9

Ian M Thompson1,*, M Scott Lucia2 and Catherine M Tangen3

1 Department of Urology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
2 Department of Pathology, University of Colorado Health Science Center, Denver, Colorado.
3 Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

* Corresponding author. Department of Urology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA. E-mail: thompsoni@uthscsa.edu

Accepted 1 March 2007

The first 150 words of the full text of this article appear below.

"What has been will be again, what has been done will be done again,; there is nothing new under the sun."

                ECCLESIASTES 1:9

It was over 70 years ago that Rich made a simple observation: prostate cancer can be found surprisingly often in asymptomatic men who succumb to other diseases.1 The prostate cancer student of today is humbled by the prescience of Rich. The context is important: Rich was a member of the faculty of the home of the discipline of Urology in the USA at Johns Hopkins. Hugh Hampton Young, MD, the ‘father of American Urology’, was the Chair and had previously described treatments for the cure of prostate cancer. Young was the first to suggest that early detection (at the time, with digital rectal examination) could identify the disease prior to metastasis, allowing surgical intervention for cure.2 Rich's observation was startlingly simple: upon pathological examination of a very . . . [Full Text of this Article]


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