IJE Advance Access originally published online on April 27, 2006
International Journal of Epidemiology 2006 35(3):527-531; doi:10.1093/ije/dyl063
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2006; all rights reserved.
Commentary |
Commentary: The analysis of variance is an analysis of causes (of a very circumscribed kind)
Programs in Science, Technology & Values and Critical & Creative Thinking, University of Massachusetts, Boston, MA 02125, USA
E-mail: peter.taylor@umb.edu
| The first 150 words of the full text of this article appear below. |
| 1974Two publications |
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The year 1974 saw the publication of two influential works by Richard Lewontin. In different ways, both addressed the measurement and characterization of genetic variation and asked whether this is interestingwhat could we explain or do with the resulting knowledge?
The Genetic Basis of Evolutionary Change1 was firmly positioned within the population genetic tradition of viewing evolution as a change of gene frequencies in a population over time. In this light it was obviously important to characterize the amount of genetic variation and account for its maintenance. Lewontin masterfully synthesized research on genetic diversity in laboratory and natural populations in relation to models of selection or its absence. At the same time he drew attention to some troublesome themes for evolutionary biology. It was not variation as such that should count, but variation that resulted in differential fitness among the variants. Yet measurements of the components of fitnesssurvival and reproductionwere
| 2006The analysis of variance and analysis of causes, revisited |
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