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IJE Advance Access originally published online on February 28, 2005
International Journal of Epidemiology 2005 34(5):972-974; doi:10.1093/ije/dyi016
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Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2005; all rights reserved.

Commentary

Commentary: Possible role of salt intake in the development of essential hypertension

Niels Graudal

Department of Internal Medicine/Rheumatology Q, Copenhagen University Hospital at Herlev, DK-2730, Herlev, Denmark. E-mail: niagr@herlevhosp.kbhamt.dk

The first 150 words of the full text of this article appear below.

Salt is one of the cornerstones on which the mammalian biochemical structure is built. Total exclusion of salt from the diet leads to disaster, namely death.1 Still, salt is considered by some authorities, to be toxic on a level comparable with alcohol and tobacco. Why is salt the only essential component of mammals to have obtained this unattractive status? As of 2004, the history behind this is exactly 100 years old and LK Dahl2 plays an important role in this history. The purpose of the present commentary is to discuss one of Dahl's papers, ‘Possible role of salt intake in the development of essential hypertension’ from 1960. To do this it is important to consider the paper in the historical context in which it was written.

The modern salt saga started in 1904 with a paper by Ambard and Brochard3 who showed an association between salt intake and blood pressure . . . [Full Text of this Article]


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Lewis Dahl and the genetics of salt-induced hypertension
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