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IJE Advance Access originally published online on November 2, 2004
International Journal of Epidemiology 2004 33(6):1183-1184; doi:10.1093/ije/dyh359
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IJE vol.33 no.6 © International Epidemiological Association 2004; all rights reserved.

Commentary

Commentary: The age distribution of cancer and a multistage theory of carcinogenesis

Richard Doll

CTSU, Harkness Building, Radcliffe Infirmary, Oxford OX2 6HE. E-mail: secretary@ctsu.ox.ac.uk

The first 10% of the full text of this article appears below.

In 1948, when I began to work with Professor Bradford Hill at the Medical Research Council's Statistical Research Unit, ideas about the causes for cancer were still dominated by those of the great German pathologists of the 19th century. A favourite idea was that cancers arose from embryonic cells that had persisted unchanged in character in adult tissues. The idea that a cancer might arise from a . . . [Full Text of this Article]


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