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IJE Advance Access originally published online on May 20, 2004
International Journal of Epidemiology 2004 33(4):628-634; doi:10.1093/ije/dyh198
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IJE vol.33 no.4 © International Epidemiological Association 2004; all rights reserved.

Editorial

Severe acute respiratory syndrome: review and lessons of the 2003 outbreak

Umesh D Parashar and Larry J Anderson

Respiratory and Enteric Viruses Branch, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta GA 30333.

Correspondence: Umesh D Parashar, Centers for Disease Control and Prevention (Mailstop A 34), Atlanta GA 30333, USA. E-mail: UAP2@CDC.GOV

The first 150 words of the full text of this article appear below.

On 11 February 2003, the Chinese Ministry of Health notified the World Health Organization (WHO) of an outbreak of atypical pneumonia that likely emerged in Guandong Province, China, in November 2002.1 During late February to early March 2003, clusters of atypical pneumonia were recognized in Vietnam, Hong Kong, Canada, and Singapore.2–6 Epidemiological investigations revealed that the index patients for each of these clusters had stayed on the ninth floor of a hotel in Hong Kong on 21–22 February (Figure 1). Further investigation indicated that the likely source of the outbreak was a physician from Guandong Province (Case A) who stayed on the same hotel floor on 21 February. This physician had cared for patients affected by the respiratory disease outbreak and he had been symptomatic with a febrile, respiratory illness since 15 February. This dramatic chain of transmission brought to the world's attention this new respiratory disease, called . . . [Full Text of this Article]

Aetiological agent

Pathogenesis and pathology

Clinical manifestations

Epidemiology

Diagnosis

Strategies for control of SARS

Conclusions


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