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International Journal of Epidemiology, Volume 33, Number 2, pp. 252
IJE vol.33 no.2 © International Epidemiological Association 2004; all rights reserved.

Commentary

Commentary: MRC Patulin trial

Ian Sutherland

The first 10% of the full text of this article appears below.

The MRC Patulin trial1 was undertaken in 1943–1944 to investigate a proposed remedy for the common cold. Only a few clinical trials took place before the second world war and they often had serious defects of planning or execution. The Patulin trial, it is claimed, was the first to meet the rigorous requirements for a scientifically . . . [Full Text of this Article]


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