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International Journal of Epidemiology 2003;32:340-341
© International Epidemiological Association 2003


Reprints and Reflections

Commentary: John Snow and alum-induced rickets from adulterated London bread: an overlooked contribution to metabolic bone disease

M Dunnigan

Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmiary, Glasgow G31 2ER, UK.

The first 10% of the full text of this article appears below.

Dr John Snow (1813–1858) is remembered for his hypothesis that cholera was communicated by contaminated drinking water. On the Mode of Communication of Cholera, published in 1849, was validated on 2 September 1854 when he persuaded the Soho parish Board of Guardians to disconnect the handle of the Broad Street pump.1 The number of cases of cholera in the parish plummeted and Snow’s fame was assured.

In contrast, Snow’s Lancet paper of 4 July 18572 suggesting that the adulteration . . . [Full Text of this Article]


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